WebApr 14, 2024 · By the end of the feeding season, an impaired antioxidant response, including reduced glutathione S-transferase activity and glutathione content, and a shift in the composition of membrane lipids, such as sterols, 18:1n-7 fatty acid, and phospholipids, were also revealed in fish fed the standard diet. WebAlpha-glutathione s-transferase and pi-glutathione s-transferase. Alpha-glutathione s-transferase (α-GST) and pi-glutathione s-transferase (π-GST) are two enzymes part of a large multigene family responsible for detoxification. These enzymes are not normally expressed or excreted in the urine (de Geus et al., 2012).
Gsta1 glutathione S-transferase, alpha 1 (Ya) [ (house mouse)]
WebAug 5, 2024 · GSTA4 is a potential surrogate biomarker for CRC screening and should provide novel approaches for chemoprevention. Title: Glutathione S-transferase alpha 4 induction by activator protein 1 in colorectal cancer. Decreased gene expression of GSTA4 is associated with drug resistance in cervical cancer. Title: Collateral sensitivity to … WebSep 4, 2024 · For glutathione S-transferase alpha 1 (GSTA1) and glutathione S-transferase mu 1 (GSTM1) polymorphisms, an association was observed with dietary fiber intake. With the use of siRNAs to compare the roles of GSTP1, GSTM2 and GSTA1 in three representative cisplatinresistant solid cancer cells, it is preliminarily concluded that GSTA … send code of practice latest version
Glutathione S-transferase: a versatile protein family
WebAbstract. Human glutathione S-transferases (GSTs) are a functionally diverse family of soluble enzymes of detoxification that use reduced glutathione (GSH) in conjugation and reduction reactions. Toxic electrophiles, including a variety of carcinogens, are substrates for the GSTs and after conjugation or reduction they are more easily excreted ... WebJul 15, 1994 · Two novel theta class glutathione S-transferases (GSTs), designated Yrs-Yrs' and Yrs'-Yrs', were isolated from rat liver cytosol and purified to homogeneity. Polyclonal antibody raised against the previously reported theta class GST Yrs-Yrs (Hiratsuka, A. et al., J. Biol. Chem. 265, 11973 (1990)) cr … WebDec 8, 2024 · Human ortholog(s) of this gene implicated in asthma and ovarian cancer. Orthologous to several human genes including GSTA1 (glutathione S-transferase alpha 1); GSTA2 (glutathione S-transferase alpha 2); and GSTA3 (glutathione S-transferase alpha 3). [provided by Alliance of Genome Resources, Apr 2024] Other designations send code of practice meaning